L.A.'s Finest follows Syd Burnett last seen in Miami taking down a drug cartel, who has left her complicated past behind to become an LAPD detective. Paired with a new partner, Nancy McKenna, a working mom with an equally complex past, Syd is pushed to examine whether her unapologetic lifestyle might be masking a greater personal secret. These two women don't agree on much, but they find common ground when it comes to taking on the most dangerous criminals in Los Angeles.