To avoid extradition, the charismatic and unpredictable drug lord Alonso Marroquin escapes from a Mexican prison to hide in a remote facility located in the middle of the desert. On the U.S. side of the border a U.S. Army experiment with minipigs conducted in a military base goes wrong and the Mexican police unit pursuing Marroquin gets infected, transforming themselves into a new enhanced zombie species with special abilities. The army and this new species converge on Marroquin's hideout where battle for survival will begin.