Gurazeni is the story of Natsunosuke Honda, a pro baseball player—a relief pitcher who has been playing pro in a team called Spiders for 8 years. The player's performance determines their annual salary and being one of the highest paid players in the game, Natsunosuke keeps an eye on the other players by reviewing their earnings. To stay on top he is always looking for players to challenge, ensuring that he performs better than them in order to keep his salary high.