With the imprisonment of Al Capone for tax evasion, Frank Nitti has taken over the operation of the organization but that isn't stopping others from trying to muscle their way in. Arnie Seeger in particular thinks he has the opportunity to create a national crime syndicate and partners with St. Louis mobster Joe Kulak to make it happen. They plan on inviting key mobsters from across the country to a conference in Chicago. Into this mix comes a recently released small-time criminal, Maxie Schram.