Jonathan Ross joins Professor Brian Cox and Dara O Briain at Jodrell Bank, home of one of Britain's biggest telescopes, for an hour of live stargazing.
The search for extraterrestrial life is the subject of Liz Bonnin's report atop one of the world's highest observatories in Hawaii, Brian chats to the crew of the International Space Station as they orbit the earth at 17,500 miles an hour, and Dara experiences what it is like to be in space.