Reigning Heisman Trophy winner Caleb Williams and No. 10 USC (6-0) visit Sam Hartman and No. 21 Notre Dame (5-2) as the Fighting Irish and the Trojans renew "the greatest intersectional rivalry" in college football in a top-25 primetime showdown.
In a rivalry that dates back to 1926, the Fighting Irish hold the all-time series advantage over the Trojans, 50-38-5. Notre Dame has won four of the past five matchups, with USC topping the Fighting Irish, 38-27, last season (Nov. 26, 2022).