Dr. Connor and his elite medical experts chopper into a frozen Arctic scientific station to probe a deadly brain affliction that climaxes when its victims fall into dementia. As a whiteout snow storm strands some of the team on the tiny base camp, Powell begins to display the same frightening symptoms. As a weakening Powell conceals the news from his family back home, Connor is sure that the source is a bacterial or fungal infection -- but the window of time to prove his theory is rapidly evaporating.