The bigger they come, the harder they fall. And when it comes to human civilizations, the modern world is as big and populous as it has ever been, so when the fall comes, it will be spectacular. The collapse of the Roman Empire was followed by roughly a thousand years of hard times for the human race. The collapse of the modern world will likely be even more traumatic.
But as history tells us and horror movies confirm, humans can survive just about anything, including world wars, global plagues, mass famines, and, maybe, a zombie apocalypse. The ones who make it through may be the horror fans who have absorbed the lessons taught by end-of-the-world spectaculars like World War Z, Train to Busan, Zombieland, War of the Worlds, I Am Legend, The Omega Man, 10 Cloverfield Lane, The World's End and The Invasion of the Body Snatchers.