In the first episode, the five patients enter the clinic for the initial four weeks of their diet, facing a host of tough challenges on the way as their ultra low-calorie diet kicks in. There's a surprise result for one patient that defies all expectations. Rosemary Shrager and Paul Sinha get some home truths about the damage being overweight is doing to their bodies, and Coleen Nolan finds out just how at risk she is of developing type 2 diabetes.