It's the penultimate round of fixtures before the end of the regular season, after which eight teams will contest the play-off places, while the other four will face a fight against relegation.
Wigan and Warrington meet at the DW Stadium. The teams met in the grand final in 2016, but a season of struggle for both has seen them spend much of the year in the bottom half of the table. They faced each other in the Challenge Cup quarter-finals in June, when only a single point separated the sides, and another close contest is expected. Castleford Tigers are looking to maintain their perfect home record when they face Salford at The Jungle. The Tigers have won all ten matches at home this season, but Salford are one of just three teams to beat them this season and need the two points to maintain their own place in the top four. Leeds take on Hull FC in the first of two titanic contests between the teams over the next few weeks. They will also meet in the Challenge Cup semi-finals at the end of the month.
Widnes are at home to Wakefield, Huddersfield face Leigh and St Helens play Catalans.