Sandra Waller, a patient in a St. Ingbert pain clinic, suffers. She makes Professor Dr. Till Pfortner, one of the most renowned surgeons in the country, is responsible for her mental crisis. Chief Inspector Palu himself witnesses when the young woman physically attacks the respected doctor on the street. While the therapist Dr. Cordula Scholz tries to free Sandra Waller not only from her pain, but also from her self-destructive trip, when a murder occurs. The doctor and painter Barbara Schreiner is shot dead - just before the vernissage of her new exhibition "Teufel im Leib". Soon thereafter, Chief Inspector Palu has to go to another crime scene: Sandra's father, the gynecologist Dr. Alfred Waller is dead at home – also shot.
The Saarbrücken "Tatort" team is investigating his latest case in the sophisticated world of plastic surgery. Chief Inspector Max Palu and his assistant Stefan Deininger stumble upon dirty deals, abysmal intrigues, strange coincidences and a hot lead to Metz behind the façade of immaculate beauty.