With aging, health consciousness and the pandemic, medicine is indispensable in our lives. Japan is actually third place in the ranking of the number of new drugs developed by a country. Further, development of drugs and quasi-drugs that are intimately tied to daily life is also common. There are over 58,000 drugstores in Japan, which is more than the number of convenience stores. Are Japan's medicine situation and the way Japanese people relate with medicine cool compared to the rest of the world? We investigate the cools of Japan's medicine in comparison to the situations in other countries.