The escape begins in Milan: Raoul Bova and Rocío Muñoz Morales, Belén and Cecilia Rodriguez, Brenda Lodigiani and Herbert Ballerina, Gué and Ernia must outrun the team of hunters led by Carlo Biffani. However, the appearance of a mysterious character leaves everyone stunned: it's the Game Master, thanks to whom hunters and fugitives come face to face from the first phase of the game.