It's all change in Aidensfield as new doctor Helen Trent arrives with her wealthy husband Matt, whilst Liz plans her wedding to Ben and departure for Kenya. With so much change at the surgery, Jenny's life begins to spiral out of control as her mind is in danger of unravelling. Merton is desperate to help, but when he does so, he finds himself on the wrong side of the law on suspicion of abusing his wife. Back at the surgery, Helen finds it hard to adjust to the slow pace of Yorkshire, and it soon becomes clear that not all is well in her marriage.