An accidental overdose of gamma radiation creates a mutation in David Banner's DNA, and, whenever he becomes angry, it causes him to metamorphose into a seven foot, 338-pound, green hulking creature. A reporter, Jack McGee, begins investigating claims of a giant monster; his investigation leads to Banner's laboratory. An explosion in the lab kills friend Elaina Marks; McGee, who dubs the creature "the Hulk", believes the Hulk killed David too. Unable to explain the truth, nor control his transformations, David leaves to try and find a cure for himself.