Nick Knowles and the team head to Barnstaple in Devon to help Jan and Lucy, whose daily four-hour round trips to hospital for life-saving dialysis treatment for two of their daughters is taking a heavy toll on family life. Along with designer Laurence Llewelyn Bowen and hundreds of local volunteers, Nick and the crew extend their house to create a home dialysis centre, enabling the girls to be treated where they live and letting the whole family settle into a healthier and happier routine.